Real Deals on Cape Girardeau hotels - save up to 88%*

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 has 2 stars with 102 rooms in Downtown - Cape Girardeau, rated 9.5 /10, "Superb".

Drury Inn & Suites Cape Girardeau has 3 stars with 87 rooms in Downtown - Cape Girardeau, rated 9.1 /10, "Superb".

Auburn Place Hotel & Suites Cape Girardeau has 2 stars with 133 rooms in Downtown - Cape Girardeau, rated 8.9 /10, "Very Good".

Drury Lodge Cape Girardeau has 3 stars with 147 rooms in Downtown - Cape Girardeau, rated 8.2 /10, "Very Good".

Cape Girardeau is situated on a hillside, and makes a handsome appearance, the great humorist and novelist Mark Twain said of our Missouri town. From ...

Pear Tree Inn Cape Girardeau Medical Center has 1 star with 78 rooms in Downtown - Cape Girardeau, rated 7.6 /10, "Good".

Americas Best Value Inn Cape Girardeau has 2 stars with 49 rooms in North Cape Girardeau - Cape Girardeau, rated 6.3 /10, "Pleasant".

Candlewood Suites Cape Girardeau has 3 stars with 85 rooms in Downtown - Cape Girardeau.

Candlewood Suites Cape Girardeau has 3 stars with 85 rooms in Downtown - Cape Girardeau.

Drury Plaza Hotel Cape Girardeau Conference Center has 3 stars with 216 rooms in North Cape Girardeau - Cape Girardeau.

Hampton Inn Cape Girardeau I-55 East MO has 3 stars with 86 rooms in Downtown - Cape Girardeau.

Hampton Inn Cape Girardeau I-55 East, MO has 2 stars with 86 rooms in Downtown - Cape Girardeau.

Town House Inn Cape Girardeau has 2 stars with 51 rooms in Downtown - Cape Girardeau.

Courtyard by Marriott Cape Girardeau Downtown with 91 rooms in Downtown - Cape Girardeau.